Figure 6.

Effect of pifithrin-α on butyrate-triggered growth inhibition and apoptosis. MCF-7 and T47-D cells were treated with 2.5 mM butyrate in the presence or absence of 20 μg ml⁻¹ pifithrin-α for 48 h. Viable cell number (A) and apoptosis (B) were determined as described in Methods. The Figure shows the results of a triplicate assay in one experiment, which is representative of three independent experiments. ^*P<0.01.