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Effect of capsaicin (0.02–200 μg) on plasma extravasation (a) and blood flow (b) in the CD1 mouse ear, measured over 60 min. Results are expressed as (a) μl of fluid accumulated per mg of ear tissue and (b) area under the flux curve (mm2), n=10. Columns show the mean size of the response, and bars show the s.e.mean. ***P<0.001 compared to ethanol-treated control values.
