Figure 3.
Comparison of effects of topical capsaicin (200 μg) on (a) plasma extravasation and (b) blood flow in the ears of wild-type (unfilled bars) and NK1 receptor knockout (black bars) Sv129+C57BL/6 mice. Results are expressed as (a) μl of fluid accumulated per mg of ear tissue and (b) area under the flux curve, n=10. Columns show the mean size of the response, and bars show the s.e.mean. *P<0.05, **P<0.01, ***P<0.001 compared to ethanol-treated control. #P<0.05 compared to capsaicin-treated wild-type.