Skip to main content
. 2002 Feb;135(4):891–900. doi: 10.1038/sj.bjp.0704528

Figure 4.

Figure 4

Effect of selective COX inhibitors on renal function in rats with cirrhosis and ascites. Urine flow (V), urinary sodium excretion (UNaV), glomerular filtration rate (GFR) and renal plasma flow (RPF) were measured before (−20 and 0 min) and up to 80 min after the i.v. administration of placebo (n=8), the selective COX-1 inhibitor (SC-560, 20 mg kg−1, n=10) or the selective COX-2 inhibitor (celecoxib, 20 mg kg−1, n=10) to rats with cirrhosis and ascites. Results are given as mean±s.e.m. Data are compared with the Student's t-test for paired data. *P<0.05; **P<0.025 and ***P<0.001 vs values at 0 min.