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Effects of selective COX inhibitors on renal water metabolism in rats with cirrhosis and ascites. The percentage (%) water load excreted (A) and the mUOsm (B) were measured before and after the administration of placebo (n=6), SC-560 (30 mg kg−1, n=7) or celecoxib (30 mg kg−1, n=8) to cirrhotic rats with ascites. Results represent the mean±s.e.m. and data are compared by the Student's t-test for paired data.
