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. 2002 Mar;135(5):1107–1114. doi: 10.1038/sj.bjp.0704488

Figure 3.

Figure 3

(A) Effect of IL-1β (1 and 5 ng paw−1, 60 min) or des-Arg9-BK (100 nmol paw−1, 20 min), given alone or after IL-1β (1 ng paw−1) i.d. injection, on MPO activity in the rat paw. (B) Effect of the co-injection of the B1 receptor selective antagonist des-Arg9-[Leu8]-BK (100 nmol paw−1) on IL-1β (1 ng paw−1, 60 min) plus des-Arg9-BK (100 nmol paw−1, 20 min)-induced increase in MPO activity in the rat paw. Each column represents the means±s.e.mean of four experiments. Significantly different from values obtained in PBS- (*), IL-1β- (#) or IL-β plus des-Arg9-BK (+) injected paws, P<0.05 (one-way ANOVA followed by Newman-Keuls test).