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The dose-effect curve (A) and the time-effect curve (B) of vasodilator responses to acetylcholine in the isolated rat thoracic aorta in the rats pretreated with native LDL. Native LDL was given intravenously. The aorta rings were precontracted by phenylephrine (10−6 M). Values are means±s.e.mean, n=6∼8. **P<0.01 compared with control.
