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Effect of probucol, vitamin E or L-arginine on endothelium-dependent relaxation to acetylcholine. Probucol and vitamin E were given orally (A). Rings was exposed to L-arginine (B). The rats were treated with LDL at the dose of 4 mg kg−1 for 48 h. Values are means±s.e.mean, n=6∼8. *P<0.05, **P<0.01 compared with LDL.
