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The temporal relationship between the daily median number (± IQR) of generalized (A) and non-generalized (B) seizures in control (shaded) and carbamazepine (CBZ; non-shaded) treated rats and CBZ and carbamazepine epoxide (CBZ-E) concentration in serum and cerebrospinal fluid (CSF) in CBZ administrated rats (4 mg kg−1 h−1; n=6 per group).
