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Effects of Z-338 on the inhibitory actions of OX-M on M type K+ current. Hyperpolarizing voltage-steps from a VH of −25 mV to −50 mV were applied to induce the M-current deactivation. In the presence of Z-338 (3×10−5 M) inhibitory action of OX-M was greatly relieved. The column show the mean value of four experiments, and vertical bars shows ±s.e.mean.
