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Effect of angiotensin II AT1 (A,B) and AT2 (C,D) receptors blockade by CV 11974 (10 nM) and PD 123319 (1 μM) respectively, on phenylephrine-induced contractions in endothelium-containing (A,C) or -denuded (B,D) aortic rings from Sprague-Dawley rats. Each point represents mean±s.e.mean generated from at least four separate experiments. *P<0.05 and **P<0.01.
