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. 2002 Apr;135(7):1641–1654. doi: 10.1038/sj.bjp.0704632

Figure 5.

Figure 5

Maximal changes in mean arterial pressure (ΔMAP) and heart rate (ΔHR) induced by 8.1 pmol BK (a) and 8100 pmol des-Arg9-BK (b) injected to the T-9 spinal cord segment of SHR and WKY without or with Hoe 140 at the dose indicated at the bottom of each column. Data are means±s.e.mean of (n) rats. Statistical comparison to aCSF values (*) or to the agonist without Hoe 140 (†) is indicated by *,†P<0.05; **,††P<0.01. Basal MAP and HR in each group were: (a) SHR: 149±3.9 mmHg and 369±11 beats min−1; WKY: 113±6.7 mmHg and 323±13 beats min−1; (b) SHR (81 pmol): 148±5.3 mmHg and 368±18 beats min−1; SHR (8100 pmol): 173±7.4 mmHg and 334±17 beats min−1; WKY: 102±9 mmHg and 310±25 beats min−1.