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. 2002 Apr;135(7):1641–1654. doi: 10.1038/sj.bjp.0704632

Figure 6.

Figure 6

Maximal changes in mean arterial pressure (ΔMAP) and heart rate (ΔHR) induced by 8.1 pmol BK (a) and 8100 pmol des-Arg9-BK (b) injected to the T-9 spinal cord segment of SHR without or with [des-Arg10]-Hoe 140 at the dose indicated at the bottom of each column. Data are means±s.e.mean of (n) rats. Statistical comparison to aCSF values (*) or to the agonist without [des-Arg10]-Hoe 140 (†) is indicated by *,†P<0.05; **,††P<0.01; †††P<0.001. Basal MAP and HR in each group were: (a) 81 pmol: 156±6.9 mmHg and 340±17 beats min−1; 810 pmol: 162±3.8 mmHg and 370±20 beats min−1; 8100 pmol: 149±10 mmHg and 358±18 beats min−1; (b) 81 pmol: 147±7.4 mmHg and 386±38 beats min−1; 810 pmol: 144±8.3 mmHg and 384±39 beats min−1; 8100 pmol: 162±6.6 mmHg and 352±15 beats min−1.