Figure 4.

Oleamide differentially enhanced GABA induced currents in both β₁ and β₂ containing recombinant receptors. (a) Trace showing the effects of oleamide on α₁β₁γ_2L GABA_A receptors (b) Trace showing the effects of oleamide on α₁β₂γ_2L GABA_A receptors. (c) Repeated measures one-way ANOVA, with a Dunnett's post test shows that cOA significantly enhanced responses in GABA receptors containing the β₁ subunit (P<0.01, n=8). (d) The β₂ subunit (P<0.01, n=8). (e) Unpaired 2-tailed Student's t-test shows that β₁ containing GABA receptors were modulated by cOA more than β₂ containing receptors (P=0.011, n=8).