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Streptavidin and DNA-biotin imaged by tapping-mode AFM in air. (A) Streptavidin at a concentration of 5 nM was allowed to adsorb to mica at 22°C for 10 min. The mica was then washed with water and air-dried. (B) DNA-biotin at a concentration of 50 nM was adsorbed to mica as in (A). Scale bars: 50 nm. A shade-height scale is shown at the bottom.
