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. 2002 Apr;135(8):1943–1950. doi: 10.1038/sj.bjp.0704660

Figure 4.

Figure 4

AFM images of streptavidin complexed with multiple DNA-biotin ligands. (A) Unoccupied streptavidin. (B) Streptavidin occupied by one DNA-biotin molecule. (C) Streptavidin occupied by two DNA-biotin molecules, with the DNA rods at an acute angle. (D) Streptavidin occupied by two DNA-biotin molecules, with the DNA rods at an obtuse angle. (E) Streptavidin occupied by three DNA-biotin molecules. (F) Streptavidin occupied by four DNA-biotin molecules, with two acute angles and two obtuse angles between the DNA rods. Scale bar: 25 nm. A shade-height scale is shown at the bottom.