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Antagonism by mesulergine (MES; A) and by SB-269970 (SB; B) of the 5-CT-induced relaxation of PGF2α-contracted longitudinal muscle preparations of dog proximal stomach. The curves represent simulations using the Hill equation and the parameters for α (shown with vertical error bars) and EC50 (shown with horizontal error bars) that were obtained from the iterative fitting procedure. The responses are expressed as percentage of muscle strip contraction to KCl (0.16 M).
