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Chronic effect of Y1 antagonist on liver weight and fat accumulation. (A) Liver weight of the vehicle- or Y1 antagonist-treated Zucker fatty rats. Values are mean±s.e.mean. (n=6). Values of Zucker lean rats are shown as a reference. (B) Microscopic observation of liver from lean, vehicle- or 100 mg kg−1 of the Y1 antagonist-treated Zucker fatty rats.
