Figure 2.

Urethane anaesthetized female rats. (A) Trace showing changes in bladder and urethral pressures, raw and integrated urethral striated muscle (EUS-EMG) activity during intravesical infusion of saline (the micturition reflex). (B) Expanded individual isovolumetric reflex-evoked bladder contraction (i.e. occurring after intravesical infusion of saline was stopped, indicated by ^* on trace A; see Methods) showing accompanying urethral relaxation, high frequency oscillations in urethral pressure and associated burst of urethral striated muscle activity. Shaded bar represents duration of intravesical infusion.