BRX-235 enhances the migration of endothelial cells inhibited by SB 203580. Migration of BAE cells was evaluated in a WMA system. Cells were co-cultivated with SB 203580 (1 μM, SB1) and BRX-235 (1000 nM, B1; 100 nM, B2; 10 nM, B3) for 48 h and the number of pixels was evaluated at 0, 4, 24 and 48 h of incubation. Data were compared to the values of migrated BAE cells attenuated by SB 1. (**P<0.01 and ***P<0.005; n=12).