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Reperfusion of the ischaemic myocardium leads to neutrophil recruitment into the myocardium (as evidenced by increased MPO levels). Neutrophil recruitment was in turn inhibited in a dose dependent manner by M40403 (0.1–1 mg kg−1). Values are mean±s.e.m. of eight experiments. *n.s.; °P<0.01 one-way ANOVA.
