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Effects of cocaine (3 μM) and the α2-adrenoceptor antagonist BRL 44408 (1 μM) on isometric contractions evoked by 10 Hz electrical stimulation for 4 s in vas deferens from wild-type or α2A/D-adrenoceptor knockout mice. Vertical bars indicate s.e. of mean from at least five experiments. Asterisks denote significance of difference from control responses (* P<0.05).
