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Relaxations of porcine coronary arteries, preconstricted with 1 μM U46619, to bradykinin (top panels) or PA-bradykinin (bottom panels) in the absence (control) or presence of 10 μM quinaprilat, following pretreatment with 4 μg ml−1 filipin, 2% cyclodextrin or 20 μg ml−1 nystatin. Data (mean±s.e.mean of 4–10 experiments) are expressed as a percentage of the contraction induced by U46619.
