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Relaxations of porcine coronary arteries, following preconstriction with 1 μM U46619, to three consecutive bradykinin doses (0.1 μM; BK1, BK2, BK3), followed by 10 μM quinaprilat, in the absence (control) or presence of 4 μg ml−1 filipin, 2% cyclodextrin or 20 μg ml−1 nystatin. Data are mean±s.e.mean of 5–12 experiments and have been expressed as a percentage of the contraction induced by U46619.
