Figure 8.

Changes in the number of eosinophils (A), neutrophils (B) and mononuclear cells (C) recovered by bronchoalveolar lavage following single and multiple antigen challenge in the Brown Norway rat. Antigen (ovalbumin)-sensitized Brown Norway rats were either unchallenged (open bars), exposed to inhaled saline (sham challenged, shaded bars) or challenged with inhaled antigen aerosol (solid bars). Animals were challenged with saline or ovalbumin once or once daily for 6 consecutive days. Group size was 7–8. Results are mean±s.e.mean. *P<0.05 compared with relevant sham challenged group.