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NO2− release in the perfusates of hearts from sensitized guinea-pigs challenged with the antigen (10 μg ovalbumin). Compared with the untreated control hearts, RLX pretreatment causes a prompt and sustained increase in NO2− amounts, whereas iRLX is ineffective. Data are expressed as mean±s.e.mean of six experiments. *P<0.05 vs control and P<0.05 RLX-treated vs iRLX-treated hearts.
