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. 2002 Oct 16;137(5):589–596. doi: 10.1038/sj.bjp.0704829

Figure 2.

Figure 2

Effects of the enantiomers WIN55,212-2 (upper right panel) and WIN55,212-3 (lower left panel), both at 1 μM, on 5-HT (30 μM; −100 mV)-induced currents obtained in one outside-out patch of a HEK 293 cell stably transfected with the h5-HT3A receptor cDNA. Drugs were applied for 3 min before, during and after stimulation with 5-HT (upper right and lower left panels). 5-HT (30 μM; −100 mV)-induced currents under control conditions (i.e. absence of a further drug; upper left panel); ‘wash' refers to the control response to 30 μM 5-HT after omission of the drug for 3 min at the end of the experiment (lower right panel).