Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2002 Oct 16;137(5):589–596. doi: 10.1038/sj.bjp.0704829

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright 2002, Nature Publishing Group

PMC Copyright notice

Influence of cannabinoid receptor ligands on 5-HT (30 μM; −100 mV)-induced currents in patches of HEK 293 cells stably transfected with the h5-HT_3A receptor cDNA. (a) Concentration-dependent inhibition by the cannabinoid receptor agonist WIN55,212-2 in the absence and presence of the CB₁ receptor antagonist SR141716A (at 1 μM) and lack of inhibition by the enantiomer WIN55,212-3 and by SR141716A alone. (b) Concentration-dependent inhibition of 5-HT (30 μM; −100 mV)-induced currents by various cannabinoid receptor ligands. Drugs were present 3 min before, during and after the 2 s 5-HT pulse. Shown are means±s.e.m. of 3–6 different patches.