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Regulation of collagen-stimulated TIMP-4 release from platelets by PGI2 and NO. Western blot (densitometry and representative insert) showing inhibition of TIMP-4 release by PGI2 (A) and GSNO (B). Data are mean±s.d., n=6. *P<0.05 treatments versus control. #P<0.05 Coll 10 versus Coll 10+GSNO 3. Control: unstimulated platelets; Coll: μg ml−1, PGI2 (nM) and GSNO (μM).
