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. 2003 Jan 7;138(1):261–271. doi: 10.1038/sj.bjp.0705028

Figure 6.

Figure 6

Effects of phosphatidylinositol-3-kinase inhibitors wortmannin and LY 294,002 and the negative control LY 303,511 (10 μM) each on NA- and SPC-induced vasoconstriction. Data are means±s.e.mean of 5–7 experiments. The following P-values for overall treatment effect were obtained for NA (P<0.0001 for LY 294,002 and LY 303,511 vs vehicle and LY 294,002 vs LY 303,511) and SPC (P=0.0018 for wortmannin vs vehicle and P=0.0060 for LY 303,511 vs vehicle) in a two-way ANOVA; *P<0.05 for individual agonist concentrations in the presence of LY 294,002 vs LY 303,511 and presence of LY 303,511 vehicle in Bonferroni post-tests.