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Response of Fura-2-loaded peritubular cells to increasing concentrations of BK. BK concentrations of 1 μM to 1 pM were used to stimulate the cells in a cuvette-based system and monitored by a photomultiplier. The basal [Ca2+]i was subtracted from the maximal Ca2+ responses (Δ[Ca2+]i). At least five experiments were averaged for each BK concentration and are graphed with their standard errors.
