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Effects of A-184209 and A-184208 in the A10 vascular smooth muscle cell line. (A) Concentration-dependence of inhibition of P1075-evoked decreases in membrane potential responses (DiBAC4(3) fluorescence) by A-184209. (B) Concentration-dependent decreases in membrane potential responses evoked by A-184208. Data in both cases were normalized to the fluorescence response evoked by 10 μM P1075. The potencies are summarized in Table 1.
