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Changes in heart rate (Δ HR) induced by SN microinjection of the vehicle (aCSF, n=8–13) or (A) the NK1 agonist [Sar9,Met(O2)11]SP (25 pmol (n=8), 100 pmol (n=4)); (B) the NK2 agonist [β-Ala8]NKA (4-10) (25 pmol (n=10), 100 pmol (n=6)) and (C) the NK3 agonist senktide (50 pmol (n=13), 100 pmol (n=6)) in SHR. Each point represents the mean±s.e.mean of (n) rats. Comparison to vehicle values is indicated by *P<0.05.
