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. 2003 Feb 19;138(4):642–654. doi: 10.1038/sj.bjp.0705096

Figure 2.

Figure 2

Changes in the escape latency in the water maze task of the nefiracetam-untreated (closed circles) and nefiracetam-treated (open circles) rats with ME, and nefiracetam-untreated sham-operated rats (open diamonds). Changes in the escape latency of the nefiracetam-treated sham-operated animals were quite similar to those of the corresponding untreated animals, as described in Table 1. Thus, the former changes are not shown in this figure. The escape latency was determined on day 7 to 9 after the ME. Each value represents the mean±s.e.mean of 10 animals. Two-way ANOVA of the data revealed significant differences in the escape latency between the sham-operated and ME rats (P<0.0001), and between nefiracetam-untreated and nefiracetam-treated rats with ME (P<0.0001). *Significantly different (P<0.05) from the sham-operated group when estimated by Fisher's post-hoc PLSD. †Significantly different (P<0.05) from the corresponding untreated ME group when estimated by Fisher's PLSD. #Significantly different (P<0.05) from the sham-operated group when estimated by Fisher's PLSD.