Figure 6.

Coapplication of 25 μM L-glutamate and D,L-TBOA did not activate group III mGluRs. (a) Group data of three experiments using paired-pulse stimulation with latency 200 ms. Relative EPSC₁-amplitude on the left-hand y-axis and EPSC₂/EPSC₁-amplitude ratio on the right y-axis. D,L-TBOA (50 μM)/L-glutamate application increased EPSC-amplitudes without affecting the facilitation. MSOP (1 mM) was without effect. (b) Averages of six traces at the indicated conditions superimposed in one experiment (a steady-state increase in I-hold of −100 pA has been subtracted for traces in TBOA/glutamate).