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Concentration–relaxation curves to ACh obtained on the thoracic aortae from healthy (open circles) rabbits and irradiated (closed circles) rabbits. The radiation dose was 6 Gy and vessels were studied 9 days later. Experiments were carried out on 24 rings from six control animals and 24 rings from six irradiated animals. Relaxations are expressed as per cent decrease in the tension evoked by 10−5 M phenylephrine. *P<0.05 compared with control responses to the same ACh concentration.
