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The haemodynamic effects of coronary artery occlusion followed by reperfusion, and administration of DDTC 5 min prior to reperfusion. DDTC was given intravenously as a single slow bolus as indicated by the arrow (50, 100 and 200 mg kg−1). *P<0.05, #P<0.01 vs before DDTC treatment (Repeated measures-ANOVA). (A) Changes in systolic arterial blood pressure. (B) Changes in mean arterial blood pressure. (C) Changes in heart rate.
