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Inhibition of [3H]-8-OH DPAT binding to human 5-HT1A serotonin receptors expressed in CHO cells by agonists. [3H]-8-OH DPAT binding was determined as described in the Methods section. The data are from representative experiments replicated as in Table 1. Data were fitted to one and two-binding site models using Prism, and the curves shown are for one-binding site models that provided the best fit to the data in all cases (P<0.05).
