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Stimulation of [35S]-GTPγS binding by agonists via human 5-HT1A serotonin receptors expressed in CHO cells. [35S]-GTPγS binding was determined as described in the Methods section. The data are from representative experiments replicated as in Table 3. Data were analysed using Prism, and the curves shown are sigmoidal concentration/response curves with Hill coefficients of 1 that provided the best fit to the data in all cases (P<0.05).
