Figure 2.
Time-course changes in the levels of tumour necrosis factor (TNF)-α, IL-1β, IL-6 and MIP-2 in bronchoalveolar lavage fluid (BALF) at 1, 3 and 15 days postbleomycin or saline in experimental groups as indicated. Treatment with N-acetylcysteine (NAC; 300 mg kg−1 per day, i.p.) reduced the augmented levels of inflammatory cytokines in bleomycin-exposed rats. Data are means±s.e.m. of four to seven animals; *P<0.05 from group A; +P<0.05 from group C.