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. 2003 Apr 11;138(7):1244–1250. doi: 10.1038/sj.bjp.0705145

Table 2.

Lack of effect of adenosine receptor antagonists on nucleotide-induced IL-8 secretion

    DPCPX CSC MRS-1220
Control 332±48 357±38 292±68 360±56
ATP 925±43 893±53 932±73 1025±73
UDP 1073±52 1002±63 1127±59 999±102
αβ-meATP 774±35 743±29 704±53 798±86
BzATP 610±53 595±59 621±47 600±34

Cells were pretreated for 30 min with the A1-receptor antagonist DPCPX or the A2a-receptor antagonist CSC or the A3-receptor antagonist MRS-1220 at a concentration of 1 μM, and were then stimulated for 24 h with 1 mM of the indicated nucleotide. Supernatants were then collected and IL-8 content was determined by ELISA. Data are expressed as mean±s.e.m. (n=3).