Skip to main content
. 2003 Apr 25;138(8):1485–1494. doi: 10.1038/sj.bjp.0705212

Table 4.

mRNA expression in the non−infarcted left ventricle (NILV), and right ventricle (RV) of the 2 week post−MI rat, and the effect of irbesartan (IRB)

  NILV RV
  MI (n=4) MI+IRB (n=4–7) MI (n=4–5) MI + IRB (n=5–9)
prepro−ANP 12±5* 25±3** 9±2* 2±1***
mRNA        
prepro−BNP 10±2* 17±4** 6±2* 1±1***
mRNA        
Fibronectin 5±1* 8±2** 4±1* 4±1**
mRNA        

mRNA data in the myocardial infarct (MI) group is presented as fold increase±s.e.m. versus sham rat. MI+IRB mRNA data is presented as fold increase±s.e.m. versus IRB−treated sham rats.

*

Represents P<0.05 versus sham rat;

**

Represents P<0.05 versus IRB−treated sham rat;

***

Represents P<0.05 versus untreated MI rat; mRNA expression was normalized to GAPDH mRNA; and (n) denotes number of rats examined.