Table 1.

Contractile parameters of skinned cardiac cells in control conditions (n=6) and in the presence of 10⁻⁸ M (n=7) or 10⁻⁵ M SR33805 (n=8), at 1.9 and 2.3 μm SL

	Control		10−8 M SR33805		10–5 M SR33805
	1.9 μm	2.3 μm	1.9 μm	2.3 μm	1.9 μm	2.3 μm
Tmax	22.0±1.2	21.0±1.3	27.8±1.3*	25.6±1.6*	24.4±2.6	22.7±3.0
nH	2.6±0.2	4.1±0.3	3.1±0.1	4.4±0.2	2.6±0.1	3.5±0.4
pCa50	5.74±0.03	6.13±0.03	5.72±0.02	6.14±0.02	5.75±0.03	6.25±0.02*
delta pCa50		0.39±0.02		0.41±0.01		0.48±0.02*

T_max is the maximal active tension in mN₀ mm⁻².

^*Indicates a significant statistical difference between the control cells versus the cells treated with SR33805 at the same SL (P<0.05).