Figure 1.

Effects of thymeleatoxin (THX) on high K⁺-induced tension in the myometria from nonpregnant and pregnant rats. Myometrial strips from nonpregnant and day 21 pregnant rats were stimulated repeatedly with 40 mM K⁺. After the response to high K⁺ was determined, THX were applied. Typical recordings of THX (10⁻⁶ M)-induced inhibition of 40 mM K⁺-induced contraction in nonpregnant (a) and pregnant (b) myometria. (c) Concentration–response courses of the inhibition induced by THX. Each point represents the mean±s.e.m. of four to five experiments. ^* Denotes significant difference from the results in nonpregnant myometrium (P<0.05).