Skip to main content
. 2003 Jun 9;139(3):598–604. doi: 10.1038/sj.bjp.0705273

Figure 4.

Figure 4

Concentration–response curves for the contractile effects evoked by PAR-1 and PAR-2 agonists on the longitudinal muscle of rat colon in the absence and in the presence of SR48968 (0.1–1 μM), NK2 receptor antagonist. SR48968 reduced in a concentration–dependent manner, the responses to both SFLLRN-NH2 and SLIGRL-NH2. The contractile effects are expressed as a percentage of the maximal contraction to carbachol (10 μM). Each value is mean±s.e.m. of at least five experiments. *P<0.05, compared to the control value.