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. 2003 Jun 9;139(3):495–500. doi: 10.1038/sj.bjp.0705275

Figure 4.

Figure 4

(a) Stimulation of cytochrome c release by BADGE. Jurkat cells were treated with 100 and 150 μM BADGE, respectively, for 4 h. Western analysis of cytochrome c expression using cytosol. Actin expression was used as control. (b) BADGE-induced cytochrome c release is not inhibited by caspase inhibitors-3, -8 and -9. Jurkat cells were pretreated for 30 min with inhibitors of caspases-3 (C3I), -8 (C8I) and -9 (C9I) (50 μM each), respectively, followed by incubation with 150 μM BADGE. Western analysis of cytochrome c expression using cytosol. Actin expression was used as control.