Figure 4.

Effects of the treatment with the nonselective selectin inhibitor fucoidin (panel a, 10 mg kg⁻¹, i.v., 15 min), an anti-CD-18 monoclonal antibody (panel b, 1 mg kg⁻¹, i.v., 15 min) or an anti-rat neutrophil antiserum (panel c, 34 μg kg⁻¹, i.p., 30 min) on des- Arg⁹-BK-induced paw oedema (100 nmol paw⁻¹) in animals pretreated with PAF (10 nmol paw⁻¹). Each point represents the mean±s.e.m. of four to six animals. In some cases, error bars are hidden within the symbols. Significantly different from control values ^*P<0.05, ^**P<0.01.