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(Panel a) Time-dependent effect of PAF treatment (10 nmol paw−1, 3–12 h) on NF-κB activation. (Panel b) Effect of the NF-κB activation inhibitor PDTC (100 mg kg−1, i.p., 30 min) or an anti-rat neutrophil antiserum (34 μg kg−1, i.p., 30 min) on NF-κB activation induced 3 h after PAF injection. Bottom: graphic representation of relative scan units. (1) PBS (2) PAF 1 h (3) PAF 3 h (4) PAF 6 h (5) PAF 12 h (6) PDTC (7) anti-PMN. Number of replicates: three.
