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. 2003 Jul 2;139(5):955–965. doi: 10.1038/sj.bjp.0705327

Figure 2.

Figure 2

Contractile response of isolated rabbit cerebral arterioles to elevated external K+ concentration and endothelin-1 (ET-1). (a, b) Plots of external diameter of arterioles against time. (a) An isolated arteriole contracted to 60 mM K+ and then partially relaxed in the continued presence of 60 mM K+. (b) ET-1 caused concentration-dependent contraction of arterioles. Concentrations are in nM. (c) Concentration–response curve for ET-1, N=number of arterioles. EC50=0.18 nM. Data shown are mean±s.e.m. and the smooth curve is the fitted Hill equation.