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. 2003 Jul 16;139(6):1153–1163. doi: 10.1038/sj.bjp.0705349

Figure 5.

Figure 5

Positively charged MTS reagent MTSET increased BKCa channel activity (at 0 mV) in a manner reversed upon washout. MTSET did not prevent the excitatory actions of NOCys. Application of MTSET (2.5 mM for 5 min) significantly increased N.Po recorded at 0 mV (a, b) as well as the BKCa channel openings at positive potentials (ci, ii). This increased in N.Po was abolished upon washout of MTSET (b). After an exposure to MTSET, NOCys (10 μM) still significantly increased BKCa channel openings at 0 mV (a, b) and positive potentials (ciii).